An alteration in the liver microsomal membrane of the rat following paracetamol overdose |
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| Authors: | H Araya T Horie M Hayashi S Awazu |
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| Affiliation: | Department of Biopharmaceutics, Tokyo College of Pharmacy, Japan. |
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| Abstract: | Fluorescence polarization of dansyl chloride covalently labelled microsomal membranes revealed an alteration in rat liver microsomal membranes following as a consequence of a paracetamol overdose. This suggests that dansyl chloride would be a useful probe in the study of the effects of paracetamol on microsomal membranes. |
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