| 颈动脉重度狭窄导致的脑梗死Hs-CRP水平及意义 |
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| 引用本文： | 尚广芹,赵洪芹,潘旭东.颈动脉重度狭窄导致的脑梗死Hs-CRP水平及意义[J].脑与神经疾病杂志,2008,16(5). |
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| 作者姓名： | 尚广芹 赵洪芹 潘旭东 |
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| 作者单位： | 山东省青岛疗养院;山东青岛大学医学院附属医院神经内科,266071 |
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| 摘 要： | 目的:探讨颈动脉颅外段重度狭窄或闭塞导致的急性脑梗塞hs-CRP水平及意义。方法:选择75例颈动脉颅外段重度狭窄或闭塞导致的脑梗塞患者和对照组30名健康体检者,采用免疫比浊法检测hs-CRP水平,分析hs-CRP水平与脑梗塞、脑梗塞局部解剖模式、颈动脉不稳定斑块、梗塞灶大小及神经功能缺损程度的相关性。结果:脑梗塞组hs-CRP水平明显高于对照组;不稳定斑块组hs-CRP水平明显高于稳定斑块组(p(0.05);大梗塞组血清hs-CRP水平显著高于中、小梗塞组,梗塞灶体积越大,血清hs-CRP水平越高,神经功能缺损程度越重(P(0.01);hs-CRP水平与脑梗塞局部解剖模式之间无相关性(P>0.05)。结论:血清hs-CRP水平增高与脑梗塞关系密切,血清hs-CRP是脑梗塞的致病因子、是脑梗塞病情严重程度的危险因子及预测因子。
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| 关 键 词： | 颈动脉颅外段重度狭窄或闭塞 急性脑梗塞 hs-CRP水平 |
Hs-CRP level and significance in patients with cerebral infarction by severe extracranial carotid stenosis |
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| SHA NG Guang-qin.Hs-CRP level and significance in patients with cerebral infarction by severe extracranial carotid stenosis[J].Journal of Brain and Nervous Diseases,2008,16(5). |
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| Authors: | SHA NG Guang-qin |
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| Institution: | SHANG Guang-qin; ZHAO Hong-qin; PAN Xu-dongQingdao university medical college; Shandong Qingdao 266071; China; |
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| Abstract: | Objective:To investigate hs-CRP level and Significance in patients with acute cerebral infarction by severe extracranial carotid stenosis and occlusion.Methods:75 patients with acute cerebral infarction and 30 healthy volunteers served as a control group were selected,their hs-CRP levels were tested with immunoturbidimetric assay,the correlation between hs-CRP levels and cerebral infarction,cerebral infarction local anatomical models,unstable carotid plaque,infarction size,neurologic functional impairment w... |
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| Keywords: | severe extracranial carotid stenosis and occlusion acute cerebral infarction hs-CRP level |
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