|
|||||
|
|
Effect of lysine vasopressin on pentylenetetrazol-induced retrograde amnesia in rats |
|
| Authors: | H B Bookin W D Pfeifer |
| Institution: | 1. Department of Psychology, Connecticut College, New London, CT 06320, USA;2. Abraham Ribicoff Research Center, Norwich Hospital, Norwich, CT 06360, USA |
| Abstract: | Lysine vasopressin (1 microgram/rat SC) administered 1 hr prior to either the acquisition trial or 24 hr retention trial facilitated passive avoidance retention. Amnesia was produced when a single 50 mg/kg (IP) injection of pentylenetetrazol was given immediately following the passive avoidance acquisition trial. A single injection of lysine vasopressin (1 microgram/rat SC) administered 1 hr prior to either the acquisition trial or 24 hr retention trial antagonized the amnesia. |
| Keywords: | Lysine vasopressin Pentylenetetrazol Amnesia Memory consolidation Memory retrieval |
| 本文献已被 ScienceDirect 等数据库收录！ | |