乳晕入路腔镜甲状腺切除术对机体创伤的临床研究

目的评价乳晕入路腔镜甲状腺切除术对机体的创伤程度。方法分析乳晕入路腔镜甲状腺切除术(实验组,23例)和开放甲状腺切除术(对照组,21例)患者围术期血浆白介素-6(IL-6)、C-反应蛋白(CRP)、皮质醇(CORT)、血糖(BG)、白细胞计数(LDC)及体温(BT)的变化,比较它们应激反应程度的不同。结果6人退出实验。每一组内各指标的含量在术后不同时点变化有统计学意义(P<0.05),两组间总体比较,各指标间差异无显著性(P>0.05)。结论乳晕入路腔镜甲状腺术和开放甲状腺术对机体造成的创伤程度相似。

Clinical study of trauma induced from endoscopic thyroidectomy with breast areola approach

[Objective] To evaluate the trauma degree of endoscopic thyroidectomy with breast areola approach. [Methods] 23 patients that received endoscopic thyroidectomy with breast areola approach formed the experimental group, while 21 patients that received open thyroidectomy formed the controlled group. Plasma levels of interleukin-6(IL-6), C-reactive protein(CRP), cortisol(CORT), blood glucose(BG), leukocyte differential count(LDC) and body temperature(BT) were measured before and at 4 hours, 24 hours, 48 hours and 72 hours after operation. [Results] All the experiments were finished except 6 patients quiting during the experiments. There was no significant difference between the parameters by comparison of the two groups as a whole. [Conclusions] The endoscopic thyroidectomy with breast areola approach and the open thyroidectomy induced the similar degree of trauma to the body.