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预激方案治疗高危组MDS
引用本文:张存业,李厚立.预激方案治疗高危组MDS[J].中国血液流变学杂志,2007,17(4):568-568,572.
作者姓名:张存业  李厚立
作者单位:江苏省沛县人民医院,江苏沛县,221600
摘    要:目的预激方案治疗高危组骨髓增生异常综合征(MDS)发病中的疗效。方法对24例高危组MDS进行预激方案治疗,并评价其疗效及不良反应。结果24例MDS患者13例达CR(54.2%),1疗程总有效率58.3%。非血液系统毒副反应较轻,中位粒缺时间6d(0~14d)。结论预激方案治疗高危组MDS疗效可靠,不良反应少,值得探索。

关 键 词:骨髓增生异常综合征  化疗  预激
文章编号:1009-881X(2007)04-0568-01
收稿时间:2007-07-20
修稿时间:2007-07-20

Patients with High-risk MDS Treated by Priming Chemotherapy
ZHANG Cun-ye,LI Hou-li.Patients with High-risk MDS Treated by Priming Chemotherapy[J].Chinese Journal of Hemorheology,2007,17(4):568-568,572.
Authors:ZHANG Cun-ye  LI Hou-li
Abstract:Objective To observe the effect and toxicy of priming chemotherapy in treatment of patients with high-risk myelodysplastic syndromes.Method 23 patients with MDS at RAEB/RAEB-t phase treated by prim-ing chemotherapy.Result 13 cases(54.2%) achieved complete remission and total effective rate was 58.3% for all the patients.The middle duration of neutrophils was 6 days(0~14 days).The treatment relative mortality was 4.3%.Conclusion Priming chemotherapy is an effective and safe treatment for MDS.
Keywords:myelodysplastic syndromes  priming chemotherapy
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