| 注射用炎琥宁与注射用头孢拉定的配伍稳定性考察 |
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| 引用本文： | 陈富超,方宝霞,李开俊,朱军,冯满.注射用炎琥宁与注射用头孢拉定的配伍稳定性考察[J].中国药房,2008,19(11):836-837. |
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| 作者姓名： | 陈富超 方宝霞 李开俊 朱军 冯满 |
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| 作者单位： | 1. 郧阳医学院附属东风总医院药学部,十堰市,442008
2. 郧阳医学院药检学院,十堰市,442000 |
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| 摘 要： | 目的:考察注射用炎琥宁与注射用头孢拉定在0·9%氯化钠注射液中的配伍稳定性。方法:采用高效液相色谱法测定注射用炎琥宁与注射用头孢拉定配伍后的含量变化,观察和检测配伍液的外观及pH值变化。结果:6h内配伍液外观、pH值及含量均无明显变化。结论:注射用炎琥宁与注射用头孢拉定在0·9%氯化钠注射液中配伍后于室温下6h内可使用。
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| 关 键 词： | 高效液相色谱法 炎琥宁 头孢拉定 配伍 稳定性 |
| 文章编号： | 1001-0408(2008)11-0836-02 |
| 修稿时间： | 2007年5月27日 |
Compatible Stability of Andrographolide for Injection with Cefradine for Injection |
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| CHEN Fu-chao,FANG Bao-xia,LI Kai-jun,ZHU Jun,FENG Man.Compatible Stability of Andrographolide for Injection with Cefradine for Injection[J].China Pharmacy,2008,19(11):836-837. |
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| Authors: | CHEN Fu-chao FANG Bao-xia LI Kai-jun ZHU Jun FENG Man |
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| Abstract: | OBJECTIVE:To study the compatible stability of andrographolide for injection with cefradine for injection in 0.9% sodium chloride injection.METHODS:The content of the mixture in 0.9% sodium chloride injection were determined at different time by HPLC;the appearance of the solution was observed and its pH value was determined.RESULTS:No significant differences were noted for the mixture in appearance,pH value and contents within 6 hours after mixing.CONCLUSION:The mixture of cefradine for injection and andrographolide for injection in 0.9% sodium chloride injection can be mixed to use within 6 h under room temperature. |
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| Keywords: | HPLC Andrographolide Cefradine Compatibility Stability |
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