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Effects of glutamine and curcumin on bacterial translocation in jaundiced rats |
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| Authors: | Oguzhan Karatepe Ersin Acet Muharrem Battal Gokhan Adas Ahu Kemik Merih Altiok Gulcin Kamali Safiye Koculu Atahan Catay Sedat Kamali Servet Karahan |
| Affiliation: | Department of Surgery Okmeydani Education and Research Hospital Department of Biochemistry Istanbul Faculty of Medicine Istanbul 34725 Turkey Department of Infectious Disease 34715 |
| Abstract: | AIM: To investigate the effect of curcumin on bacterial translocation and oxidative damage in an obstructive jaundice model and compare the results to glutamine, an agent known to be effective and clinically used. METHODS: Twenty-four female Wistar-Albino rats, weighing 200-250 g, were randomly divided into three groups (8 in each group). After ligation of the common bile duct in all animals, GroupⅠ received oral normal saline, Group Ⅱ received oral glutamine and Group Ⅲ received oral curcumin for seven day... |
| Keywords: | Obstructive jaundice Bacterial translocation Oxidative damage Glutamine Curcumin |
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