大气颗粒物污染对儿童肺功能影响的多因素分析

本文对大气颗粒物污染程度不同的3个地区504名儿童进行肺功能测定,采用逐步回归分析年龄、身高、大气颗粒物污染、被动吸烟等14个因素对FVC、FEV_1、FEF25-75％和FEF75-85％4项肺功能测定指标的影响。结果表明,大气颗粒物污染能引起FEF25-75％和FEF75-85％的减小,较长期暴露干颗粒物污染情况下,儿童的肺功能受到一定程度的损害。用力呼气流量,尤其是用力呼气末段流量(FEF75-85％)能较敏感地反映颗粒物污染对儿童肺功能的影响。

Multifactor Analysis of Particulate pollution in Air of on Pulmonary Function of Children

Pulmonary function tests were performed on 504 children in three regions of different level of particle pollution in air. Spirometric indexes (FVC, FEV_1, FEF_(25-75%) and FEF_(75-85%)) were determined by using stepwise regression anglysis to 14 factors such as age, height, PPA and passive smoking etc. The decrease in FEF_(25-75%) and FEF_(75-85%) were observed in children living in polluted areas. The result indicated that long-term exposure to particle pollution had an adverse effe- cts on children's lung function. Forced expiratory flows, especially forced end expiratory flow were sensitive in reflecting the effects of particle poll- ution in air on children's pulmonary function.