| 刺猬蛋白信号通路与成骨的关系 |
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| 引用本文： | 关呈超,蒋欣泉,张富强.刺猬蛋白信号通路与成骨的关系[J].国际口腔医学杂志,2009,36(2). |
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| 作者姓名： | 关呈超 蒋欣泉 张富强 |
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| 作者单位： | 上海交通大学医学院附属第九人民医院口腔修复科,上海,200011 |
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| 基金项目： | 上海市重点学科建设项目 |
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| 摘 要： | 刺猬蛋白(hedgehog)信号通路是一个在胚胎阶段调控多种组织器官发育的重要的信号通路,在成骨方面具有重要的作用.下面主要就hedgehog信号通路及其对成骨相关细胞的作用、hedgehog在骨组织发育中的作用、hedgehog基因修饰在成骨中的应用作一综述.
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| 关 键 词： | 刺猬蛋白 信号通路 成骨 |
The relationship between hedgehog signaling pathway and osteogenesis |
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| GUAN Cheng-chao,JIANG Xin-quan,ZHANG Fu-qiang.The relationship between hedgehog signaling pathway and osteogenesis[J].Journal of International Stomatology,2009,36(2). |
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| Authors: | GUAN Cheng-chao JIANG Xin-quan ZHANG Fu-qiang |
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| Abstract: | Hedgehog signaling pathway is an important signal pathway,which regulates the development of vari-ety of tissues and organs in the embryonic stage. It also plays an important role in osteogenesis. This review dis-cussed the relationship between the hedgehog signaling pathway and osteogenesis in several aspects,including the relationship between the hedgehog and osteochondral cell,the effect of hedgehog on bone development and the role of hedgehog in osteogenesis with gene therapy techniques. |
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| Keywords: | hedgehog signaling pathway osteogenesis |
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