The role of miRNA-210 in pre-eclampsia development |
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| Authors: | Ilona Jaszczuk,Dorota Koczkodaj,Adrianna Kondracka,Anna Kwaś niewska,Izabela Winkler,Agata Filip |
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| Affiliation: | aDepartment of Cancer Genetics with Cytogenetic Laboratory, Medical University of Lublin, Lublin, Poland;bDepartment of Obstetrics and Pathology of Pregnancy, Medical University of Lublin, Lublin, Poland;cSecond Department of Gynecological Oncology, St. John’s Center of Oncology of the Lublin Region, Lublin, Poland |
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| Abstract: | MicroRNAs (miRNAs) are a class of small non-coding, single-stranded RNAs (ribonucleic acids) that play important roles in many vital processes through their impact on gene expression. One such miRNA, miR210, represents a hypoxia-induced cellular miRNA group that hold a variety of functions. This review article highlights the importance of miR-210 in the development of pre-eclampsia.KEY MESSAGE- miR-210 is a promising biomarker for monitoring pregnancy with pre-eclampsia. Overexpression of miR-210 had a negative impact on the process of cell migration and trophoblast invasion.
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| Keywords: | miR-210 hypoxia pre-eclampsia |
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