Two successful pregnancies in a 46,XY patient

Two successful pregnancies (singleton followed by twins) following ovumdonation/in-vitro fertilization in a 46,XY woman have been studied.Although similar cases have previously been presented: in a pure XY patientand in a 45,X/46,XY patient, this case is one in which a subsequentsuccessful pregnancy has resulted. In such patients, the rate of Caesareansection appears to be increased, and we postulate that the hypoplasticnature of the uterus, although able to respond quite well to both exogenousand endogenous hormones to accept and maintain a pregnancy, may lack thecapability to respond fully in labour by dilating appropriately.