危重新生儿应激性高血糖症71例临床分析

目的提高儿科医生对危重新生儿血糖监测的重视，及时治疗、减少脑损害。方法71例应激性高血糖患儿采用微量血糖仪取末梢血测血糖，2h测1次，直至血糖恢复正常。血糖7．0～14．0mmol／L 11例，仅限制用糖。重度高血糖60例随机分为治疗组30例，对照组30例，治疗组用胰岛素治疗。结果重度高血糖治疗组及对照组应用胰岛素治疗24h及72h后比较差异有统计学意义（t=7．9、4．27，P〈0．001）。结论轻、中度高血糖采用限制用糖，即可较快恢复正常。重度高血糖应用胰岛素治疗，血糖下降较快，可尽快纠正由于血糖升高所致的高渗血症，对改善危重新生儿预后有重要意义。

Clinical analysis of 71 cases of neonatal stress hyperglycemia

Objective To improve focus of pediatrician on blood sugar monitoring in severe newborn and perform immediate therapy and decrease brain damage. Methods In seventy-one newborn with stress hyperglycemia, using microsaccharimeter,blood sugar in peripheral blood was detected once every 2 hours until blood sugar was recovered to the normal level, 11 cases,blood sugar ranged from 7.0 to 14.0mmol/L,were restricted from sugar,sixty cases of severe hyperglycemia were randomly divided into treatment group( n =30) and control group( n = 30) ,and insulin was administered in treatment group. Results Efficacy had significant difference 24 hours and 72 hours late by treatment with insulin in treatment group of severe hyperglycemia and control group( t = 7.9,4.27 ,P<0.001). Conclusions Blood sugar is quickly decreased into the normal level in newborn with modest-moderate hyperglycemia performed with restriction from sugar,administration of insulin in severe hyperglycaemia newborn quickly decrease blood sugar, rectifies hyperosmosisemia induced by increment of blood sugar and plays a very important role in improving of sever newborn.