| 冠心病患者幽门螺杆菌感染与斑块特征、脂代谢、炎症反应的相关性 |
| |
| 引用本文： | 黄勇,李蔚华,尹虹,饶红. 冠心病患者幽门螺杆菌感染与斑块特征、脂代谢、炎症反应的相关性[J]. 中国动脉硬化杂志, 2019, 27(8): 713-717 |
| |
| 作者姓名： | 黄勇 李蔚华 尹虹 饶红 |
| |
| 作者单位： | 华中科技大学同济医学院附属梨园医院心内科 |
| |
| 摘 要： | 目的探讨冠心病患者幽门螺杆菌(Hp)感染与斑块特征、脂代谢、炎症反应的相关性。方法选取2017年8月至2019年3月本院首诊的冠心病患者178例作为研究对象,根据Hp感染检测结果进一步分为Hp阳性组65例、Hp阴性组113例。对比2组冠心病患者冠状动脉造影结果、颈动脉超声斑块特征,以及外周血脂代谢指标、血清炎症介质水平的差异。结果冠状动脉造影结果显示,2组冠心病患者的冠状动脉病变支数、斑块性质差异有统计学意义(P0.05)。Hp阳性组Gensini积分大于Hp阴性组(P0.01)。Hp阳性组的颈动脉超声斑块面积、内膜中膜厚度大于Hp阴性组(P0.01);2组斑块性质差异有统计学意义(P0.05)。Hp阳性组血总胆固醇、低密度脂蛋白胆固醇水平高于Hp阴性组,高密度脂蛋白胆固醇水平低于Hp阴性组(P0.01)。Hp阳性组血清白细胞介素6、白细胞介素18、肿瘤坏死因子α、高敏C反应蛋白水平高于Hp阴性组(P0.05)。结论合并Hp感染可能是导致冠心病患者斑块稳定性下降、脂质代谢紊乱加剧、炎症反应加重的重要因素之一。
|
| 关 键 词： | 冠心病 幽门螺杆菌 斑块特征 脂代谢 炎症反应 |
| 收稿时间： | 2019-02-13 |
| 修稿时间： | 2019-03-19 |
Relationship between Helicobacter pylori infection and plaque characteristics, lipid metabolism, inflammatory response in patients with coronary heart disease |
| |
| HUANG Yong,LI Weihu,YI Hong and RAO Hong. Relationship between Helicobacter pylori infection and plaque characteristics, lipid metabolism, inflammatory response in patients with coronary heart disease[J]. Chinese Journal of Arteriosclerosis, 2019, 27(8): 713-717 |
| |
| Authors: | HUANG Yong LI Weihu YI Hong RAO Hong |
| |
| Affiliation: | Department of Cardiology, Liyuan Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430077, China,Department of Cardiology, Liyuan Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430077, China,Department of Cardiology, Liyuan Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430077, China and Department of Cardiology, Liyuan Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430077, China |
| |
| Abstract: | |
| |
| Keywords: | coronary heart disease Helicobacter pylori plaque characteristics lipid metabolism inflammatory response |
| 本文献已被 CNKI 等数据库收录！ |
| 点击此处可从《中国动脉硬化杂志》浏览原始摘要信息 |
|
点击此处可从《中国动脉硬化杂志》下载全文 |
|
