| 终末期肝病模型联合总胆汁酸对亚急性肝衰竭患者预后的评估 |
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| 引用本文： | 王晓韧,颜炳柱,杨宝山.终末期肝病模型联合总胆汁酸对亚急性肝衰竭患者预后的评估[J].临床肝胆病杂志,2011,27(6):638-640. |
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| 作者姓名： | 王晓韧 颜炳柱 杨宝山 |
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| 作者单位： | 哈尔滨医科大学附属第二医院感染科,哈尔滨,150001 |
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| 摘 要： | 目的探讨终末期肝病模型（MELD）联合血清总胆汁酸（TBA）的检测对于判断亚急性肝衰竭患者预后的意义。方法亚急性肝衰竭患者110例,测定血清肌酐（CR）,TBil,凝血酶原时间国际标准化比值（INR）,TBA,根据公式计算MELD值,单一评估MELD,TBA及二者联合对亚急性肝衰竭患者预后的判断价值。结果恶化死亡组的MELD值及TBA均明显高于好转治愈组（P〈0.05）,MELD值、TBA值各组间病死率的比较具有统计学意义（P〈0.01）。将MELD值≥30,TBA值≥200联合判断患者病死率的敏感性和特异性分别为67.65%,97.37%,MELD值与TBA值呈正相关（r=0.9903,P〈0.01）。结论 MELD分值联合TBA可以提高亚急性肝衰竭患者预后判断的准确性
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| 关 键 词： | 肝功能衰竭 胆汁酸类和盐类 终末期肝病模型 |
The prognostic assessment of model for end-stage liver disease(MELD) and total bile acids in patients with subacute liver failure |
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| WANG Xiao-ren,YAN Bing-zhu,YANG Bao-shan.The prognostic assessment of model for end-stage liver disease(MELD) and total bile acids in patients with subacute liver failure[J].Chinese Journal of Clinical Hepatology,2011,27(6):638-640. |
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| Authors: | WANG Xiao-ren YAN Bing-zhu YANG Bao-shan |
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| Institution: | WANG Xiao-ren,YAN Bing-zhu,YANG Bao-shan.(Department of Infention Disease,the Second Affiliated Hospital of Harbin Medical University,Harbin 150001,China) |
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| Abstract: | Objective To analyze the effect of combination of MELD with total bile acids on predicting the prognosis of subacute liver failure.Methods Serum CR,INR,TBil and TBA of 81 patients with subacute liver failure were detected and MELD scores were calculated by the formula.The single scores of MELD or total bile acids and the two kinds of scores together were compared.Results The level of MELD and total bile acids of patients in death group were higher than that in survival group(P<0.05).There were significant d... |
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| Keywords: | liver failure bile acids and salts model for end-stage liver disease |
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