异丙酚静脉麻醉在颅脑外伤手术中的应用体会

（目的）比较民丙酚与硫喷妥钠在静脉麻醉诱导时意识消失时间、气管插管反应及清醒时间（停止注药到拔管）。（方法）选择Glasgow评分8分以上的颅脑外伤手术患者60例，随机分为两组。A组用异丙酚麻醉，B组用硫喷妥钠麻醉。（结果）A组意识消失时间明显快于B组（P＜0．05），气管插管评级两组比较差异无显著性（P＞0．05）。A组清酷暑时明显快于B组，两组间差异有非常显著性（P＜0．01）。（结论）异丙酚作用快、维持时间短、体内无蓄积、毒性小、恢复迅速平稳，是一种安全有效的静脉麻醉药。

Study on the application of propofol intravenous anesthesia on craniocerebral trauma operations

[Object] to compare the unconsciousness time, the intubation reaction and the time of reviviscence time of the patients applied with induction with propofol and thiopental sodium. [Method] 60 cases of craniocerebral trauma patients who scored over 8 points of Glasgow were randomly divided into two groups. Group A was applied with propofol and the group B sodium thiopental. [Result] It showed that the time of unconsciousness of group A was earlier than group B (P.0. 05) and so was the time of reviviscence (P,0.01) , but the two groups had no significant discrepancy of the intubation reaction (P.0.05) [Conclusion] Propofol is a safe and effective intravenous anesthesia. It effect quickly, lasts long, cumulate none in the body, has little toxicant and recovers well.