孟鲁司特钠致四肢麻木震颤和呼吸困难

1例45岁女性患者因慢性支气管炎急性发作，给予左氧氟沙星静脉滴注（0.4 g，1次/d），并给予苏黄止咳胶囊（3粒，3次/d）及孟鲁司特钠（10 mg，1次/d，睡前）口服。患者首次口服孟鲁司特钠10 mg后约30 min，出现四肢麻木震颤、呼吸困难、全身乏力，继而出现恶心、呕吐，持续约2h无缓解。停服孟鲁司特钠，左氧氟沙星和苏黄止咳胶囊继续应用，同时给予相应对症处理。观察至次日下午16：00，患者四肢麻木震颤、呼吸困难症状缓解，未再出现恶心、呕吐。

Numbness of extremities,tremor,and dyspnea induced by montelukast sodium

A 45-year-old woman received an intravenous injection of levofloxacin（ 0. 4 g,once daily）,Suhuangzhike（苏黄止咳）capsules（3 capsules,thrice daily）by mouth,and montelukast sodium （10 mg at bedtime,once daily）by mouth for acute attack of chronic bronchitis. About 30 min after the first administration of montelukast sodium,the patient developed numbness of extremities and tremor,dyspnea, and generalized weakness,followed by nausea and vomiting and the symptoms lasted for about 2 hours without alleviating. Montelukast sodium was discontinued,levofloxacin and Suhuangzhike capsules were applied continuously,and symptomatic treatments were given at the same time. The numbness of extremities and tremor and dyspnea relieved,nausea and vomiting did not recur until 16 ：00 of the following day.