立体定向引导氩氦刀靶向冷冻治疗脑胶质瘤

目的 探索应用氩氦外科冷冻系统结合脑立体定向外科治疗脑胶质瘤的手术疗效。方法使用ＣＲＷ立体定向仪，行头颅计算机体层摄影扫描（ＣＴ）确定脑胶质瘤中心及边缘点坐标。以氩氦超冷治疗探针在限定靶区进行冷冻－复温－冷冻治疗４例复发性胶质瘤。结果 １例直径４．５ｃｍ的颞部肿瘤行钻孔肿瘤中心靶点冷冻治疗；余３例直径８￣１５ｃｍ枕顶部肿瘤行立体定向等体积切除手术，术中冷冻后切除冷冻瘤组织；术后ＣＴ扫描显示：３例肿

Cryosurgery of cerebral gliomas with cryocare surgical system guided by stereotactic technology

Objective To investigate the effects of treating brain glioma patients with cryosurgical system gUided by stereotactic technology. Method Using CRW stereotactic instrument and brain CT to define the center and endge coordinate of brain glioma. The cryocare probe was carried out to treat 4 cases recurred glioma at the limited target by freezing, re-warming and freezing. Result One patients, with the diameter of the glioma was 4.5cm, accepted the cryocare surgery from drilled skull hole with no resection; the other 3 patients, with the diameter of gliomas ranged from 7 to 15cm, were taken stereotaxy-assisted craniotomy and removed the necrotic tissue after cryotherapy. Post-operative CT image showed that all glioma tissue and 1cm of the scope of external tumor tissue were eliminated in 3 cases, No cerebral hemorrhage and remarkable cerebraledema; The case which was carried out directive cryocare surgery was found out that the dye of the focus was vanished and the dense of CT was descended. One patient aggravated mild hemiplegia afer operation, and recovered soon. one patient whose skin incision didn't heal well was carried out the scalp skin-petal transition operation and the skin incision healed quickly. Conclusion Stereotactic guided cryocare surgical system can remove brain tumor totally with less trauma and hemorrhage than the conventional way. It is also a safe method for the management of hrain glioma. So it may have encouraging future in the clinical application, though its long term effects still need to be observed further.