护牙素在正畸治疗中对减少牙齿脱矿及促进再矿化的功效研究

目的评价Tooth Mousse护牙素对减少离体牛牙粘接托槽周围的釉质脱矿及促进再矿化的功效。方法将60颗粘接托槽的离体牛牙随机分成实验组、阳性对照组和阴性对照组，分别在牙面上涂擦Tooth Mousse护牙素、Duraphat氟保护漆和蒸馏水。将3组样本轮流放置入人工致龋液和人工唾液中浸泡，然后使用偏光显微镜、扫描电镜、电子探针检测。结果偏光显微镜下观察，实验组釉质表面完整，主要表现为以脱矿为主的正性双折射区明显减少；扫描电镜观察实验组釉质表面有大量的矿物质沉积，填补釉质表面局限性的小凹陷；电子探针检测结果显示，实验组釉质表面钙、磷含量明显高于阴性对照组（P<0.05），与阳性对照组之间无统计学差异（P>0.05）。结论Tooth Mousse护牙素在体外实验模型中能使牛釉质在人工致龋环境中减少脱矿和促进再矿化。

Efficacy of Tooth Mousse in reducing enamel demineralization and promoting remineralization

Objective To evaluate the efficacy of Tooth Mousse in reducing enamel demineralization lesions adjacent to bonded orthodontic brackets and promoting remineralization in vitro.Methods 60 bovine teeth with bonded orthodontic brackets were randomly divided into three groups,negative control group,positive control group and experimental group,applied separately with distilled water,Duraphat fluoride varnish,Tooth Mousse.3 groups were dipped into an artificial caries solution and an artificial saliva solution,cycling between them.All samples were detected by polarized light microscope,scanning electron microscope and electron probe micro-analysis.Results Po-larized light microscope showed that the enamel surface of the experimental group were completed,the areas of posi-tive birefringence were decreased obviously.Scanning electron microscope showed that a large number of deposits were found on the dental enamel surface of the experimental group,filled in the small local concave of enamel surface.Compared with the control group,electron probe micro-analysis showed that calcium and phosphate concentration of enamel surface was higher in experimental group than in negative control group(P<0.05),there was no significant differences between experimental group and positive control group(P>0.05).Conclusion Tooth Mousse can reduce enamel demineralization and promoting remineralization in vitro.