姜黄的化学成分研究Ⅰ:没药烷型倍半萜

目的研究姜黄中的化学成分。方法利用正相硅胶柱色谱、反相ODS柱色谱及反相高效液相色谱等多种分离方法对姜黄的体积分数80％乙醇提取物进行分离鉴定。结果与结论分离得到6个倍半萜类化合物，通过理化性质和波谱数据鉴定它们的结构分别为：turmeronol A（1）、turmeronol B（2）、bisabolone（3）、8-hydroxyl—arturmemne（4）、bisabolone-9-one（S），（6S）-2-methyl-6-（1R，5S）-（4-methene-5-hydroxyl-2-cyclohexen）-2-hepten-4-one]（6）。其中，化合物6为新的天然产物，化合物5为首次从该属植物中分离得到。同时，利用DEPF-135、HSQC、HMBC等核磁技术对化合物3的化学位移进行了准确归属。对文献中报道的数据归属进行了更正。

Chemical constituents of Curcuma longa Ⅰ: bisabolane sesquiterpenes

Aim To study the chemical constituents of Curcuma longa.Methods The 80% EtOH extract was isolated by means of silica gel,ODS column chromatography and reverse phase high performance liquid chromatography(RP-HPLC).Results and conclusions Six sesquiterpenes were isolated and identified as turmeronol A(1),turmeronol B(2),bisabolone(3),8-hydroxyl-ar-turmerone(4),bisabolone-9-one(5),and (6S)-2-methyl-6-(1R,5S)-(4-methene-5-hydroxyl-2-cyclohexen)-2-hepten-4-one](6).Compound 6 was firstly isolated from this plant,which represents a new natural product and compound 5 was isolated for the first time from this genus.In addition,the carbon and proton signals of compound 3 were assigned unambiguously based on 1H-NMR,13C-NMR,DEPT-135,HMQC,and HMBC spectra,and some assignments reported in the literature were revised.