伞状支撑骨移植术治疗股骨头坏死的生物力学研究

目的 观察伞状支撑骨移植术治疗股骨头坏死的生物力学变化.方法 应用伞状支撑骨移植术(A组)治疗山羊股骨头坏死模型,并通过生物力学检测与单纯股方肌骨柱移植术组(B组)、骨髓间充质干细胞和松质骨移植术组(C组)进行对照研究(每组均14只).结果 术后3个月A组手术侧股骨头软骨下骨、松质骨的最大压强和弹性模量为:(77.43±2.65)、(120.60±4.18)MPa;(46.63±1.32)、(81.74±3.96)MPa.高于B组、C组(P＜0.05),与正常侧比较差异无统计学意义(P＞0.05).结论 伞状支撑骨移植术能有效恢复股骨头的生物力学强度,防止塌陷.

A biomechanical study on treatment of osteonecrosis of the femoral head by umbrella strut bone grafting

Objective To observe the biomechanical changes for treatment of the osteonecrosis of femoral head by umbrella strut bone grafting. Methods The femoral-head osteonecrosis models on one side were subjected to umbrella strut bone grafting and bone marrow mesenchymal stem cells transplantation (group A). The goats in group B received simple unit side muscle bone flap grafting, and those in group C received umbrella strut bone grafting and cancellous bone grafting transplantation. A control study for three groups (14 goats of each group) was conducted by biomechanics examination. Results After 3 months, the biomechanics examination showed that the maximum compressive strength and average elastic modulus of sub-chondral bone and cancellous bone in group A were ( 77.43 ± 3.65), ( 120.60 ± 4.18 ) Mpa; (46.63 ± 1.32) , (81.74 ±3.96) Mpa, which were statistically significantly higher than in groups B and group C ( P <0.05 ) , while the difference had no statistically significant difference comparing to the unaffected sides (P > 0.05). Conclusion Umbrella strut bone grafting could effectively restore the biomechanical strength and prevent the collapse of femoral head.