3D-FSPGR动态增强联合DWI诊断肝内小结节病变

目的：探讨三维快速扰相梯度回波（3D-FSPGR）序列MRI动态增强扫描和扩散加权成像（DWI）对肝内小结节病变的诊断价值。方法：对56例经US或CT检查发现肝内小结节的患者行常规MRI平扫、3D-FSPGR动态增强及DWI检查（SPEPI技术，b值分别为0和800s／mm^2）。对比分析3D-FSPGR三期增强扫描（A组）、DWI（B组）及这2种方法联合应用（C组）在结节检出和定性诊断方面的价值。结果：在结节检出方面：A组检出61个结节，B组检出49个，C组检出72个，3组间差异有极显著性意义（χ^2=27．72，P〈0．01）；A组与B组比较，差异无显著性意义（χ^2=5．54，P〉0．05）；A组、B组分别与C组比较，差异均有显著性意义（χ^2值分别为11．91和27．37，P〈0．01）。在结节的定性诊断方面：在取得临床或病理证实的52个病例中，A组诊断正确36例（69．2％），C组为47例（90．4％），2组间差异有显著性意义（χ^2=7．21，P〈0．05）。结论：联合应用3D-FSPGR动态增强扫描和DWI对肝内小结节病灶的检出和诊断具有重要的临床应用价值。

Application of 3D-FSPGR Dynamic Enhanced MRI in Combination with Diffusion Weighted Imaging in the Diagnosis of Intra-hepatic Small Nodular Lesions

Objective:To study the value of 3D FSPGR dynamic enhanced MRI in combination with diffusion weighted imaging(DWI) in the diagnosis of intra-hepatic small nodular lesions.Methods:56 cases with intra-hepatic small nodular lesions detected by Utrasonography or CT were examined by routine conventional and 3D FSPGR dynamic enhanced MRI in combination with DWI(SE/EPI technique,b value as 0 and 800s/mm2 respectively).The values of detection and diagnosis of intra-hepatic small nodular lesion by 3D-FSPGR tri-phase ...