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Post-operative chemotherapy for ovarian carcinoma: a prospective study with cyclophosphamide |
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| Authors: | A Akinkugbe V E Uguru V P Mordi |
| Affiliation: | 1. Department of Obstetrics and Gynaecology, College of Medicine, Idi-Araba, P.M.B. 12003, Lagos Nigeria;2. Department of Morbid Anatomy, College of Medicine, Idi-Araba, P.M.B. 12003, Lagos Nigeria |
| Abstract: | Seventy consecutive patients with carcinoma of the ovary were managed in our unit by laparotomy and extensive debulking procedures over a period of 8 years. Intensive post-operative chemotherapy was given with intravenous cyclophosphamide. The mean follow-up period was 2.6 years. Our results showed that 19 patients with early disease (stages I and II) showed complete remission but seven subsequently died of recurrent disease. The others with more advanced disease showed little response to treatment. |
| Keywords: | Cyclophosphamide Carcinoma of ovary Laparotomy and debulking procedures Post-operative chemotherapy Remission Dead of recurrent disease Advanced disease, little response |
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