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正交试验法优选乳腺丸剂的制备工艺
引用本文:兰恭赞,刘高峰,滕宇宏.正交试验法优选乳腺丸剂的制备工艺[J].黑龙江医药,2006,19(6):465-466.
作者姓名:兰恭赞  刘高峰  滕宇宏
作者单位:哈尔滨医科大学附属第二医院药学部,黑龙江,哈尔滨,150086
摘    要:目的:研究影响乳腺丸硬度的因素,解决乳腺丸在制备和存放过程中坚硬的问题。方法:采用正交试验法考察药粉粒度、蜂蜜用量、蜂蜜含糖量、丸块放置时间四因素对乳腺丸硬度的影响。结果:在影响乳腺丸硬度的因素中,蜂蜜用量为主要因素,丸块放置时间次之,药粉拉度和蜂蜜合糖量影响最小。结论:在实际生产中,用80目的药粉与室糖度为80度的蜂蜜1:1混合放置12h,乳腺丸软硬度最为适宜。

关 键 词:乳腺丸  硬度  正交试验法
文章编号:1006-2882(2006)06-465-02
收稿时间:2006-05-18
修稿时间:2006年5月18日

Optimization of the Preparation Technology of Mammary Gland Pill with Orthogonal Experiment
Lan Gongzan,Liu Gaofeng,Teng Yuhong.Optimization of the Preparation Technology of Mammary Gland Pill with Orthogonal Experiment[J].Heilongjiang Medicine,2006,19(6):465-466.
Authors:Lan Gongzan  Liu Gaofeng  Teng Yuhong
Institution:Department of Pharmacy, the ,Second Affiliated Hospital of Harbin Medical University , Harbin, Heilongjiang, 150086
Abstract:To explore the racers that affect the hardness of mammary gland pill and solve the issue that the pill became too hard during preparation and storage Methods:Using orthogonal experiment,We investigated the effects of par- ticle,the dosage and saccharinity of honey,place time on the hardness of the pill.Results:Among the factors,the dosage of honety was the major one and place time was of the second place; while the factors of the particle and saccharinity of honey were of little importance.Conclnsion:When 80 objective medicine poweder mixes with 80% saccharinity of honey at rate of 1:1 for 12h,the degree of hardness of marmmary gland piular is optimal during practical production.
Keywords:mammary gland pill  hardness  ortogonal experiment  
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