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外科手术在小细胞肺癌治疗中的价值
引用本文:Ye B,Zhao SH,Liu XY. 外科手术在小细胞肺癌治疗中的价值[J]. 癌症, 2007, 26(7): 795-797
作者姓名:Ye B  Zhao SH  Liu XY
作者单位:中国医学科学院中国协和医科大学肿瘤医院胸外科,北京,100021;中国医学科学院中国协和医科大学肿瘤医院胸外科,北京,100021;中国医学科学院中国协和医科大学肿瘤医院胸外科,北京,100021
摘    要:与非小细胞肺癌相比较,小细胞肺癌具有更快的肿瘤倍增时间、快速生长以及易于早期转移的特点.以往认为小细胞肺癌的患者不适合手术,小细胞肺癌的主要治疗是化疗和放疗.但是许多研究表明手术对于早期局限型的小细胞肺癌患者有益,特别是T2N0的患者,同时手术治疗能够防止其局部复发.但临床分期超过T2N0的患者,手术无益于患者的长期生存.对于手术治疗适合哪一期小细胞肺癌的患者、手术如何联合化疗以及手术的方式仍然值得进一步研究.

关 键 词:肺肿瘤/外科手术  小细胞肺癌  疗效
文章编号:1000-467X(2007)07-0795-03
修稿时间:2006-11-272007-02-07

The role of surgical resection in treating small cell lung cancer
Ye Bo,Zhao Shou-Hua,Liu Xiang-Yang. The role of surgical resection in treating small cell lung cancer[J]. Chinese journal of cancer, 2007, 26(7): 795-797
Authors:Ye Bo  Zhao Shou-Hua  Liu Xiang-Yang
Affiliation:Department of Thoracic Surgery, Cancer Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100021, P. R. China
Abstract:Compares with non-small cell lung cancer,small cell lung cancer (SCLC) generally has a more rapid doubling time,a higher growth fraction,and earlier development of widespread metastases. Surgical operation has little impact on long-term survival of SCLC patients. Chemotherapy with combined radiotherapy has been recommended as the main treatment of SCLC. Patients with SCLC in excess of stage T2N0 do not benefit from surgical operation. But some data suggest the potential benefit of surgcial resection in the few patients with very limited disease,especially peripheral T1-2N0 lesions. Surgical resection can also prevent the recurrence of local disease. The role of surgical resection in the management of SCLC remains to be defined.
Keywords:Lung neoplasm/surgical operation   Small cell lung cancer   Efficacy
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