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脑出血后凝血酶的神经毒性作用
引用本文:肖兵,胡长林. 脑出血后凝血酶的神经毒性作用[J]. 国际脑血管病杂志, 2004, 12(12): 911-913
作者姓名:肖兵  胡长林
作者单位:400010,重庆医科大学附属第二医院神经内科;400010,重庆医科大学附属第二医院神经内科
摘    要:脑出血是神经内科常见急症。脑出血后,在血肿及其周围产生大量凝血酶。内源性凝血酶是 一种神经毒性物质,可引起脑组织一系列的病理生理学改变。文章就凝血酶的一般特性和其神经毒 性作用作了综述。

关 键 词:凝血酶  脑出血  血脑屏障  脑水肿
修稿时间:2004-10-10

Neurotoxic Effects of Thrombin After Intracerebral Hemorrhage
Xiao Bing,Hu Changlin. Neurotoxic Effects of Thrombin After Intracerebral Hemorrhage[J]. International Journal of Cerebrovascular Diseases, 2004, 12(12): 911-913
Authors:Xiao Bing  Hu Changlin
Affiliation:Xiao Bing,Hu Changlin Department of Neurology,the Second Affiliated Hospital of Chongqing University of Medical Sciences,Chongqing 400010,China
Abstract:Intracerebral hemorrhage is a common neurological emergency. A large amount of thrombin produced in hematoma and its surrounding tissues after intracerebral hemorrhage. The endogenous thrombin is a kind of neurotoxic agent which causes a series of pathophysiological changes. The article reviews the general characteristics of thrombin and its neurotoxic effects.
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