子宫肌瘤药物治疗 |
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引用本文: | 杨欣. 子宫肌瘤药物治疗[J]. 中国实用妇科与产科杂志, 2012, 28(12): 905-908 |
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作者姓名: | 杨欣 |
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作者单位: | 作者单位:北京大学人民医院妇产科,北京100044 |
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摘 要: | 目前尚无治疗子宫肌瘤的有效药物。促性腺激素释放激素激动剂(GnRHa)能改善术前贫血症状,但费用高并可导致低雌激素状态。芳香化酶抑制剂和选择性雌激素受体调节剂(SERM)在绝经后有症状的子宫肌瘤治疗中有效。使用米非司酮治疗,闭经率高,副反应小。左炔诺孕酮宫内节育系统(LNG IUS)可治疗子宫肌瘤合并月经过多。
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关 键 词: | 子宫肌瘤 促性腺激素释放激素激动剂 米非司酮 左炔诺孕酮宫内节育系统 |
Medical therapy for uterine leiomyoma |
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Abstract: | There is no effective medical therapy to date. GnRHa are useful pre operatively. Aromatase inhibitors and SERM may be useful in postmenopausal woman with symptomatic myoma. Low dose mifepristone is a relatively cheap drug with minimal side effects. The use of Levonorgestrel releasing intrauterine system has been shown to reduce menstrual blood loss with idiopathic menorrhagia or menorrhagia due to leiomyomas. |
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Keywords: | uterine myoma gonadotrophin-releasing hormone analogues mifepristone LNG-IUS |
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