| 纳洛酮治疗急性脑梗死的临床疗效观察 |
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| 引用本文： | 经屏,张媚,张临洪,闻立斗. 纳洛酮治疗急性脑梗死的临床疗效观察[J]. 中国中西医结合急救杂志, 2003, 10(2): 118-119 |
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| 作者姓名： | 经屏 张媚 张临洪 闻立斗 |
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| 作者单位： | 武汉市中心医院神经科,湖北,武汉,430014 |
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| 摘 要： | 目的 :观察纳洛酮治疗急性脑梗死的临床疗效。方法 :将 88例急性脑梗死患者按随机数字表法分为纳洛酮组 (治疗组 )与胞二磷胆碱组 (对照组 )治疗 14d,观察其临床疗效以及神经功能缺损评分的变化。结果 :治疗组总显效率为 6 7.9% ,总有效率为 85 .7% ,与对照组比较均有显著性差异 (分别为 31.3%和 6 8.8% ,P<0 .0 1和 P<0 .0 5 ) ;治疗后神经功能缺损评分显著减低 ,显著优于对照组 ( P<0 .0 1)。结论 :纳洛酮治疗急性脑梗死疗效好 ,安全性高 ,可促进神经功能恢复。
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| 关 键 词： | 纳洛酮 脑梗死 急性 胞二磷胆碱 |
| 文章编号： | 1008-9691(2003)02-0118-02 |
| 修稿时间： | 2003-01-27 |
Clinical study of therapeutic effect of naloxone in acute cerebral infarction |
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| JING Ping,ZHANG Mei,ZHANG Linhong,WEN Lidou. Clinical study of therapeutic effect of naloxone in acute cerebral infarction[J]. Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care, 2003, 10(2): 118-119 |
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| Authors: | JING Ping ZHANG Mei ZHANG Linhong WEN Lidou |
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| Affiliation: | JING Ping,ZHANG Mei,ZHANG Linhong,WEN Lidou.Department of Neurology,Wuhan Central Hospital,Wuhan 430014,Hubei,China |
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| Abstract: | Objective:To observe the effect of naloxone in acute cerebral infarction.Methods:Eightyeight cases were randomly divided into naloxone group (trial group) and nicholine group (control group).The effect of naloxone and the changes of neurological deficit scale score at 14 days after treatment were evaluated. Results:The effective rate and the total effective rate in trial group were 67.9% and 85.7% as compared with control group(31.3% and 68.8%),there were significantly difference between the two groups( P<0.01 and P<0.05).After treatment,neurological deficit scale scores in trial group were significantly lower than those in control group.Conclusion:Our study suggest that naloxone is effective and safe for acute cerebral infarction,with promoting neurological recovery. |
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| Keywords: | naloxone acute cerebral infarction nicholine |
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