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Estado actual del valor pronóstico de los marcadores moleculares en pacientes con cáncer colorrectal y la predicción de respuesta al tratamiento adyuvante |
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| Authors: | Jose M Fernández-Cebrián Peter Vorwald Kuborn Mar Pardo de Lama Alfonso Sanjuanbenito Dehesa Manuel Nevado Santos Pedro A Pacheco Martínez Beatriz Fernández-Escudero |
| Institution: | 1. Servicio de Cirugía General y Aparato Digestivo, Hospital Ramón y Cajal, Madrid, Espa?a 2. Unidad de Cirugía General y Aparato Digestivo, Fundación Hospital Alcorcón, C/Budapest, 1 Alcorcón, 28922, Madrid, Espa?a 3. Unidad de Anatomía Patológica, Fundación Hospitla Alcorcón, Madrid, Espa?a 4. Facultad de Ciencias de la Salud, Universidad Rey Juan Carlos, Espa?a |
| Abstract: | Colorectal cancer is one of the best studied of all malignant diseases interms of genetics and/or molecular prognostic factors. These factors, and relationships with prognosis, may have important implications especially in the design of surgical and adjuvant chemo-radiotherapy options. However, the true prognostic significance of all known factors has yet to be realised. We have reviewed the literature with specific focus on the role of molecular markers involved in prognosis and the prediction of response to adjuvant treatment. |
| Keywords: | cáncer colorrectal factores pronósticos moleculares |
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