原发性高血压肝阳上亢证证治规律探讨

肝阳上亢证是原发性高血压的常见证型 ,与胰岛素抵抗增强、酪氨酸羟化酶基因过度表达、血小板α-颗粒膜蛋白分泌异常、血管内皮细胞损伤、红细胞变形能力降低、微循环障碍和垂体 -性腺激素分泌异常密切相关 ,其病机演变有内在规律 ,证候表现有自身特点 ,治疗以平肝潜阳为法。从而为平肝潜阳法治疗原发性高血压提供了理论依据

Discussion on clinical manifestation and administration in primary hypertention caused by liver-yang hyperactivity

Liver-yang hyperactivity is a main pathogere of primary hypertention The disease is also relevant with insulin resistance,phenotype of gene TH over-expression,disorder of secretive function in granular membrane protein,lesions in vascular endocullar cells,decrease of deformation ability of erythrocyte,disorder in microcirculation,abnormal changes in hypophysis and sexual hormone So,the clinical manifestation of primary hypentention caused by liver-yang hyperactivity has varity of symptoms,and the therapeutic principle is to soothe liver to subdue yang