| 掌叶大黄鞣质类化学成分研究 |
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| 引用本文： | 邓瑞雪,黄玉阳,张玉秀,陆世鹏,孟文娟,张雨,刘普. 掌叶大黄鞣质类化学成分研究[J]. 中草药, 2020, 51(4): 908-911 |
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| 作者姓名： | 邓瑞雪 黄玉阳 张玉秀 陆世鹏 孟文娟 张雨 刘普 |
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| 作者单位： | 河南科技大学化工与制药学院洛阳市天然产物功能因子研究及产品开发重点实验室, 河南 洛阳 471023,河南科技大学化工与制药学院洛阳市天然产物功能因子研究及产品开发重点实验室, 河南 洛阳 471023,河南科技大学化工与制药学院洛阳市天然产物功能因子研究及产品开发重点实验室, 河南 洛阳 471023,河南科技大学化工与制药学院洛阳市天然产物功能因子研究及产品开发重点实验室, 河南 洛阳 471023,河南科技大学化工与制药学院洛阳市天然产物功能因子研究及产品开发重点实验室, 河南 洛阳 471023,河南科技大学化工与制药学院洛阳市天然产物功能因子研究及产品开发重点实验室, 河南 洛阳 471023,河南科技大学化工与制药学院洛阳市天然产物功能因子研究及产品开发重点实验室, 河南 洛阳 471023 |
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| 基金项目： | 国家自然科学基金-河南省联合基金（U1604192）；河南省高校科技创新人才支持计划项目（20HASTIT008） |
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| 摘 要： | 目的研究掌叶大黄Rheum palmatum根中鞣质类化学成分。方法采用硅胶柱色谱、中压柱色谱及半制备高效液相色谱等多种色谱分离方法对鞣质类成分进行分离,根据波谱数据分析鉴定化合物结构。结果从掌叶大黄的70%乙醇提取物中分离得到4个鞣质类化合物,分别鉴定为3-O-桂皮酰基-1-O-没食子酰基-β-D-葡萄糖苷(1)、2-O-桂皮酰基-1-O-没食子酰基-β-D-葡萄糖苷(2)、2-O-桂皮酰基-1,6-O-二没食子酰基-β-D-葡萄糖苷(3)、6-O-桂皮酰基-1-O-没食子酰基-β-D-葡萄糖苷(4)。结论化合物1为新化合物,命名为掌叶大黄苷。
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| 关 键 词： | 掌叶大黄 鞣质类化合物 掌叶大黄苷 2-O-桂皮酰基-1-O-没食子酰基-β-D-葡萄糖苷 6-O-桂皮酰基-1-O-没食子酰基-β-D-葡萄糖苷 |
| 收稿时间： | 2019-07-18 |
Chemical constituents of tannin from roots of Rheum palmatum |
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| DENG Rui-xue,HUANG Yu-yang,ZHANG Yu-xiu,LU Shi-peng,MENG Wen-juan,ZHANG Yu and LIU Pu. Chemical constituents of tannin from roots of Rheum palmatum[J]. Chinese Traditional and Herbal Drugs, 2020, 51(4): 908-911 |
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| Authors: | DENG Rui-xue HUANG Yu-yang ZHANG Yu-xiu LU Shi-peng MENG Wen-juan ZHANG Yu LIU Pu |
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| Affiliation: | Luoyang Key Laboratory of Natural Products Functional Factor Research and Development, College of Chemical Engineering&Pharmaceutical, Henan University of Science and Technology, Luoyang 471023, China,Luoyang Key Laboratory of Natural Products Functional Factor Research and Development, College of Chemical Engineering&Pharmaceutical, Henan University of Science and Technology, Luoyang 471023, China,Luoyang Key Laboratory of Natural Products Functional Factor Research and Development, College of Chemical Engineering&Pharmaceutical, Henan University of Science and Technology, Luoyang 471023, China,Luoyang Key Laboratory of Natural Products Functional Factor Research and Development, College of Chemical Engineering&Pharmaceutical, Henan University of Science and Technology, Luoyang 471023, China,Luoyang Key Laboratory of Natural Products Functional Factor Research and Development, College of Chemical Engineering&Pharmaceutical, Henan University of Science and Technology, Luoyang 471023, China,Luoyang Key Laboratory of Natural Products Functional Factor Research and Development, College of Chemical Engineering&Pharmaceutical, Henan University of Science and Technology, Luoyang 471023, China and Luoyang Key Laboratory of Natural Products Functional Factor Research and Development, College of Chemical Engineering&Pharmaceutical, Henan University of Science and Technology, Luoyang 471023, China |
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| Abstract: | Objective To study the chemical constituents of tannin from the roots of Rheum palmatum. Methods Chemical constituents of tannins were isolated by silica gel column chromatography, medium pressure column chromatography, and semi-preparative HPLC from the roots of R. palmatum. The structures were elucidated on the basis of spectral data analysis. Results Four tannins, 3-O-cinnamoyl-1-O-galloyl-β-D-glucopyranoside(1), 2-O-cinnamoyl-1-O-galloyl-β-D-glucopyranoside(2), 2-O-cinnamoyl-1,6-di-O-galloyl-β-D-glucopyranoside(3), and 6-O-cinnamoyl-1-O-galloyl-β-D-glucopyranoside(4) were isolated from the roots of R. palmatum. Conclusion Compound 1 is a new compound named palmatoside. |
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| Keywords: | Rheum palmatum L. tannins palmatoside 2-O-cinnamoyl-1-O-galloyl-β-D-glucopyranoside 6-O-cinnamoyl-1-O-galloyl-β-D-glucopyranoside |
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