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60例胆囊癌的临床分析及预后
引用本文:任刚,马林,于国,刘丽威. 60例胆囊癌的临床分析及预后[J]. 世界肿瘤杂志, 2008, 7(3): 204-206
作者姓名:任刚  马林  于国  刘丽威
作者单位:[1]中国人民解放军总医院放疗科,北京100853 [2]中国人民解放军总医院病理科,北京100853 [3]中国人民解放军总医院肿瘤科,北京100853
摘    要:目的回顾性分析胆囊癌病人的临床病理资料并进行随访,探讨其临床病理特征及影响病人术后生存的因素。方法收集解放军总医院1999年7月至2005年7月间经手术切除并具有完整资料的原发性胆囊癌病例。回顾性分析胆囊癌病人的临床、病理资料,进行单因素及多因素预后分析。结果最终成功获得完整临床病理资料及随访资料的胆囊癌病人共60例,单因素分析显示病人Nevin分期、肿瘤分化程度、血管侵犯、肿瘤有无坏死及手术方式均为影响预后的因素。Cox多因素分析表明肿瘤的病理分期以及手术方式是影响病人术后生存时间的独立因素。结论影响胆囊癌病人术后生存的独立因素仅为肿瘤的病理分期以及手术方式。

关 键 词:胆囊癌  预后  多因素分析

Analysis and prognostic study of 60 cases with gallbladder carcinoma
Affiliation:REN Gang, MA Lin, YU Guo, LIU Li-wei (1 Department of Radiation Oncology;2 Department of Pathology; 3 Department of Oncology, General Hospital of PLA, Beijing 100853, China)
Abstract:Objective To identify clinicopathologic characteristics and prognostic factors through a retrospective analysis of clinicopathological data of gallbladder carcinoma patients. Methods Gallbladder carcinoma patients surgically treated from 1999 to 2005 in our hospital were followed up and studied by univariate and multivariate analysis. Results 60 cases were followed up. Using univariate analysis, Nevin stage, tumor differentiation, necrosis, invasion of vascular and surgical manage all showed significant correlation to prognosis. In Cox multivariant survival analysis, Nevin stage and surgical treatment were independent prognostic indicators. Conclusions Independent prognostic factors of survival after gallbladder carcinoma operation might be Nevin stage and surgical methods.
Keywords:Gallbladder carcinoma  prognosis  multivariate analysis
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