| 龟芪散及其拆方对免疫抑制小鼠IL-2产生及其基因转录的影响 |
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| 引用本文： | 朱晓新,吴敦序,王露.龟芪散及其拆方对免疫抑制小鼠IL-2产生及其基因转录的影响[J].中国实验方剂学杂志,1998,4(5):15-18. |
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| 作者姓名： | 朱晓新 吴敦序 王露 |
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| 作者单位： | 中国中医研究院西苑医院(朱晓新)，上海中医药大学(吴敦序)，山东临沂医专(王露) |
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| 摘 要： | 龟芪散及其拆方可明显增强Ｃｙ所致免疫受损小鼠Ｔ淋巴细胞的增殖；提高Ｌ３Ｔ＋４细胞数量及Ｌ３Ｔ＋４／Ｌｙｔ＋２细胞比率；促进脾细胞ＩＬ－２ｍＲＮＡ转录和ＩＬ－２产生。以全方效果最佳，亦好于ＰＳＰ。但对正常小鼠无明显影响。
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| 关 键 词： | 龟芪散 拆方 淋巴细胞 白细胞介素－2 |
| 收稿时间： | 1997/9/15 0:00:00 |
Effects of Guiqi Powder and Its Simplified Formula on IL-2 mRNA and Protein Expression Level of Immunosuppressed Mice |
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| Zhu Xiaoxin,Wu Dunxu,Wang Lu.Effects of Guiqi Powder and Its Simplified Formula on IL-2 mRNA and Protein Expression Level of Immunosuppressed Mice[J].China Journal of Experimental Traditional Medical Formulae,1998,4(5):15-18. |
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| Authors: | Zhu Xiaoxin Wu Dunxu Wang Lu |
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| Institution: | 1Xiyuan Hospital,China Academy of TCM,Beijing,100091;2Shanghai University of TCM,Shanghai,200032;3Linyi Medical College,Linyi,276002 |
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| Abstract: | Guiqi powder as a whole and its simplified formulae could promote significantly the proliferation of T lymphocytes,increase L3T+4 cells counts raise ratio of L3T+4/Lyt+2 cells and enhance spleen cells IL-2 mRNA and protein expression level in immunosuppressed mice caused by cyclophosphamide.The original Guiqi powder as a whole was more potent than its simplified formula as well as PSP.However it showed no effects in normal mice. |
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