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疏肝理脾片抗大鼠免疫性肝纤维化研究
引用本文:孙克伟,刘伟士,谌宁生,王伟华,刘明德. 疏肝理脾片抗大鼠免疫性肝纤维化研究[J]. 中国实验方剂学杂志, 1998, 4(3): 28-30
作者姓名:孙克伟  刘伟士  谌宁生  王伟华  刘明德
作者单位:湖南中医学院第一附属医院
基金项目:国家科委“八五”攻关项目
摘    要:用牛血清白蛋白(BSA)造成大鼠免疫损伤性肝纤维化模型,观察疏肝理脾片对肝纤维组织增生程度、肝羟脯氨酸(Hyp)含量和血清透明质酸(HA)及肝功能的影响。结果表明疏肝理脾片能明显降低肝Hyp含量,减轻肝纤维组织增生程度,并较好地提高血清白蛋白水平

关 键 词:肝纤维化  疏肝理脾片
收稿时间:1997-04-10

Study of Shugan Lipi Tablet on Anti hepatic Fibrosis Induced by Bovine Serum Albumin in Rat
Sun Kewei,Liu Weishi,Chen Ninsheng,Wang Weihu,Liu Mingde. Study of Shugan Lipi Tablet on Anti hepatic Fibrosis Induced by Bovine Serum Albumin in Rat[J]. China Journal of Experimental Traditional Medical Formulae, 1998, 4(3): 28-30
Authors:Sun Kewei  Liu Weishi  Chen Ninsheng  Wang Weihu  Liu Mingde
Affiliation:The First Affiliated Hospital of Hunan College of TCM,Changsha,410007
Abstract:Objective:To observe the effect of anti-hepatic fibrosis of Shugan Lipi tablet.Method:Immuno injured fibrosis was induced in rats by bovine serum albumin.The contents of hydroxyproline(Hyp) in liver and serum hyaluronic acid (HA) and other liver function were monitored.Results:The Hyp content and degree of hepatic fibrosis in Shugan Lipi tablet-treated groups were remarkably decreased,compared with the control group,and the serum albumin level significantly increased.
Keywords:hepatic fibrosis  Shugan Lipi tablet
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