| 以大剂量环磷酰胺为主治疗上腔静脉综合征临床分析 |
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| 引用本文： | 牟玲,陈为志.以大剂量环磷酰胺为主治疗上腔静脉综合征临床分析[J].四川肿瘤防治,2000,13(3):173-175. |
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| 作者姓名： | 牟玲 陈为志 |
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| 作者单位： | 山东省日照市人民医院,日照 |
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| 摘 要： | 目的：采用以大剂量环磷酰胺（ＨＤ－ＣＴＸ）主为联合化疗方案治疗由恶性肿瘤引起的上腔静脉综合征（ＳＶＣＳ）。方法：ＳＶＣＳ３２例，其中中肺癌与胸腺癌１５例选用ＣＡＰ方案，恶性淋巴瘤６例选用ＡＢＣＯＰ方案。结果：恶性淋巴瘤ＣＲ６６．６７％（４／６），ＰＲ３３．３３％（２／６）。ＳＣＬＳ ＣＲ２８．５７％（４／１４），ＰＲ３５．７１％（５／１４），ＮＣ２８．５７％（４／１４），ＰＤ７．１４％（１／１４）
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| 关 键 词： | 上腔静脉综合征 环磷酰胺 治疗 纵隔肿瘤 |
Clinical analysis of high-dose cytoxan in treating patient with SVCS |
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| MU Ling,CHEN Wei-zhi,LIU Hai-rong,et alRizhao People's Hospital,Rizhao.Clinical analysis of high-dose cytoxan in treating patient with SVCS[J].Sichuan Journal of Cancer Control,2000,13(3):173-175. |
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| Authors: | MU Ling CHEN Wei-zhi LIU Hai-rong Rizhao People's Hospital Rizhao |
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| Institution: | MU Ling,CHEN Wei-zhi,LIU Hai-rong,et alRizhao People's Hospital,Rizhao 276826 |
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| Abstract: | Objective:To study the efficacy of high-dose cytoxan (CTX) based combined chemotherapy in treating the patients with superior vena cava syndrom (SVCS)caused by malignant tumors.Methods:Patients with lung cancer or malignant thymoma were treated with CAP regimen.Maliglant lymphoma patients were treated with ABCOP regimen.Rusults:The response rates were:lymphoma CR 66.67%(4/6),PR 33.33%(2/6);SCLC CR 28.57%(4/14),PR 35.71%(5/14),NC 28.57%(4/14),PD 7.14%(1/14),NSCLC CR 9%(1/11),PR 36.36%(4/11),NC 36.36%(4/11),PD 18.18%(2/11) malignant thymoma NC(1/1).The response rate of SVCS in two days was 21.9%(7/32) ;43.8% (14/32) from three to five days;18.8% (6/32) from 5 to 7 days;15.6% (5/32) beyond seven days.Conclusion:The high-dose CTX was effective and well tolerated in treating the cancer patients with SVCS. |
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| Keywords: | SVCS CTX Chemotherapy |
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