Effect of emodin and sandostatin on metabolism of eicosanoids in acute necrotizing pancreatitis |
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| Authors: | Wu Jian-Xin Xu Jia-Yu Yuan Yao-Zong |
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| Institution: | 1. Department of Gastroenterology, Shanghai First People′ s Hospital,Shanghai 200080, China
2. Ruijin Hospital, Shanghai Second Medical University, Shanghai 200025, China |
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| Abstract: | INTRODUCTION In order to study the therapeutic mechanisms of emodin, an extract of Rhubarb (Rhizoma et Radix Rhei, a traditional Chinese herbal medicine), and sandostatin in the treatment of acute necrotizing pancreatitis (ANP), we used the two drugs in rat models of the disease and observed the changes of plasma thromboxane-2 (TXB2),6-ketoprostaglandin F1α (6-keto-PGF1α) and prostaglandin E2 (PEG2). |
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| Keywords: | pancreatitis eicosanoids metabolism emodin sandostatin |
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