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The regulatory role of Nrf2 in antioxidants phase2 enzymes and IL-17A expression in patients with ulcerative colitis |
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| Authors: | Milad Sabzevary-Ghahfarokhi Mojtaba Shohan Hedayatollah Shirzad Ghorbanali Rahimian Amin Soltani Mahdi Ghatreh-Samani Fatemeh Deris Nader Bagheri Mohammedhadi Shafigh Kamran Tahmasbi |
| Affiliation: | 1. Department of Microbiology and Immunology, Faculty of Medicine, Shahrekord University of Medical Sciences, Shahrekord, Iran;2. Cellular and Molecular Research Center, Basic Health Sciences Institute, Shahrekord University of Medical Sciences, Shahrekord, Iran;3. Department of Internal Medicine, Shahrekord University of Medical Sciences, Shahrekord, Iran;4. Medical Plants Research Center, Basic Health Sciences Institute, Shahrekord University of Medical Sciences, Shahrekord, Iran;5. Department of Epidemiology and Biostatistics, School of Health, Shahrekord University of Medical Sciences, Shahrekord, Iran;6. Department of Pathology, Shahrekord University of Medical Sciences, Shahrekord, Iran |
| Abstract: | |
| Keywords: | ROS reactive oxygen species UC ulcerative colitis Nrf2 nuclear factor erythroid 2 related factor 2 IBD inflammatory bowel diseases DSS dextran sodium sulfate IL-17 interleukin-17 APE1 apurinic/apyrimidinic endonuclease PRDX1 peroxiredoxin-1 GST-A4 4-HNE trans-4-hydroxy-2-nonenal IEC intestinal epithelial cells COPD chronic obstructive pulmonary disease Hmox-1 heme oxygenase-1 RORct retinoic orphan receptor gamma(t) MAPK mitogen-activated protein kinase Oxidative stress Ulcerative colitis Nrf2 GST-A4 PRDX1 |
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