颅内神经节细胞胶质瘤的临床、病理及MRI表现分析

目的分析颅内神经节细胞胶质瘤的临床、病理及MRI表现。方法收集我院经病理确诊颅内神经节细胞胶质25例,分析病灶部位、数量、平扫及增强信号特点、瘤周水肿情况,以探析MRI影像特点。结果 25例患者中,22例为癫痫发作,其中19例以癫痫为唯一临床表现、3例为失神发作。2例为囊性、10例为囊实性、13例为实性。T1WI上囊性患者以低信号为主,实性患者以等信号或稍低信号为主,囊实性患者两类信号兼有。T2WI上囊性患者以高信号为主,实性患者为等信号或稍高信号,囊实性患者两类信号兼有。增强扫描囊性患者无强化,实性患者以轻度强化为主,囊实性患者以明显强化及轻度强化为主。1例无水肿、15例轻度水肿、4例中度水肿、5例重度水肿。结论颅内神经节细胞胶质瘤多以癫痫发作为主,可分为囊性、囊实性及实性3种类型,不同类型患者具有不同MRI表现,结合病理特点可为临床诊治提供指导。

Analysis of Clinical Pathological and MRI Findings of Intracranial Ganglioglioma

Objective To analyze the clinical, pathological and MRI findings of intracranial ganglioglioma.Methods 25 patients with intracranial ganglioglioma confirmed by pathology in our hospital were selected as the research object. The location, quantity, signal characteristics of plain scan and enhanced scan and peritumoral edema were analyzed to explore the MRI imaging findings.ResultsIn the 25 patients, there were 22 cases with epilepsy seizures, including 19 cases whose only clinical manifestation was epilepsy and 3 cases was absence seizures. There were 2 cases with cystic lesions, 10 cases with cystic solid ones and 13 cases solid ones. Patients with cystic lesions mainly showed low signal on T1WI while patients with solid ones mainly showed equal signal or slightly low signal and patients with cystic solid ones showed both two types of signals. Patients with cystic lesions mainly showed high signal on T2WI while patients with solid ones mainly showed equal signal or slightly high signal and patients with cystic solid ones showed both two types of signals. Enhanced scan showed there was no enhancement in patients with cystic or solid lesions and there was mild enhancement in patients with solid ones and obvious enhancement and mild enhancement in patients with cystic and solid ones. There were 1 case without edema, 15 cases with mild edema, 4 cases with moderate edema and 5 cases with severe edema.Conclusion The main manifestation of intracranial gangliogliomas is epilepsy seizure, which can be divided into cystic, cystic solid and solid of 3 types. Different types of patients have different MRI findings. Combined with pathological features, it can provide guidance for clinical diagnosis and treatment.