DTI成像技术在脊髓震荡损伤中的应用价值

目的探讨弥散张量成像(DTI)在脊髓震荡损伤中的应用价值。方法收集脊髓震荡损伤17例作为研究组(A组),32例非脊髓震荡髓损伤的脊髓损伤病例作为对照组(B组);选取与A、B组年龄、部位相匹配的49例健康志愿者作为对照组(C组)。所有病例行MR平扫和DTI扫描,测量A组和B组脊髓损伤节段平均FA值和平均ADC值,测量C组(与前2组相同节段脊髓)平均FA值和平均ADC值,并分析A组与C组、A组与B组组间差异。结果 B组平均ADC值为(1301.35±221.15)×10-6mm2/s,平均FA值为(377.12±67.31)×10-3;C组平均ADC值为(827.63±218.54)×10-6mm2/s,平均FA值为(540.03±38.14)×10-3。A组平均ADC值(1103.25±49.65)×10-6mm2/s,较C组升高,有统计学意义(P0.05),较B组降低(P0.05),有统计学意义;A组平均FA值(423.53±58.42)×10-3,较C组下降,有统计学意义(P0.01),较B组升高,有统计学意义(P0.05)。结论 DTI对脊髓震荡伤有较高的敏感性,对脊髓损伤的分级诊断有重要意义。

Application Value of Diffusion Tensor Imaging In Spinal Cord Concussion Injury

Objective To investigate the application values of DTI in spinal cord concussion injury(SCC).Methods Routine MR scan and DTI were accomplished in 17 cases of SCC, study group A, and 32 cases of spinal cord injury without SCC, control group B, and also in 49 cases of healthy volunteers occupied same ages and spinal cord segments with group A and B, normal control group C. Average FA values and ADC values at the injury segments of group A and B, and also at the same segments with group A and B in group C were calculated. The Average differences of FA values and ADC values between group A and B, and also between group A and group C were analyzed.Results The significantly statistical difference of increased average ADC value (1103.25±49.65)×10-6mm2/s and decreased average FA value(423.53±58.42)×10-3 in group A than average ADC value(827.63±218.54)×10-6mm2/s and average FA value (540.03±38.14)×10-3in group C were found. The significantly statistical difference of decreased average ADC value and increased FA value in group A compared with the average ADC value (1301.35±221.15)×10-6mm2/s and average FA value (377.12±67.31)×10-3 in group B existed.Conclusion DTI is highly sensitive to SCC and possess important significance in grading diagnosis of spinal cord injury.