64层螺旋CT评估冠脉狭窄与左心室功能的临床应用研究

目的探讨64层螺旋CT用于评估冠状动脉狭窄与左室心功能相关性的临床应用价值。方法以77例冠状动脉狭窄患者作为研究对象,将其作为观察组,另选28例同期进行健康体检且无冠状动脉狭窄者作为对照组进行研究。所有受检者均接受64层螺旋CT和二维超声心动图左室功能检查,分别对采用两种方法所测得的两组患者的左室功能参数进行分析。结果 77例患者经64层螺旋CT与二维超声心动图检查所测得的EDV值、ESV值、SV值、EF值经Peasorn相关性检验表示具有良好的一致性,r=0.72-0.85。EDV值、ESV值、EF值、MM值与冠状动脉狭窄程度呈显著正相关(r=0.21、0.45、0.49、0.42,p0.05);SV值各组间差异均无统计学意义,与冠脉狭窄程度不具有相关性(r=0.07,P0.05)。结论64层螺旋CT同时评估冠状动脉狭窄与左室功能具有高度可行性,可准确评价冠脉狭窄对左室心功能造成的损害,狭窄程度越严重左心功能损害越大,可为临床治疗提供重要依据。

Clinical Research on 64-slice Dynamic Volume CT Evaluation Applied in Coronary Artery Stenosis and Functions of Ventriculus Sinister

Objective To explore the value of 64-slice dynamic volume CT used for assessment of coronary artery stenosis and the correlation of cardiac function of left ventricular.Methods Seventy seven patients with coronary artery stenosis were selected as research subjects, and they were divided into the observation group, 28 candidates undergoing healthy physical examinations without coronary artery stenosis were selected into the control group for research. All subjects underwent 64-slice dynamic volume CT and two-dimensional echocardiography on left ventricular function, and left ventricular function parameters of two groups of patients were analyzed respectively by use of two methods.Results ESV value, EDV value, SV value and EF value measured by 64-slice & 64-lamina dynamic volume CT with two-dimensional echocardiography via Peasorn correlation inspection showed good consistency (r=0.72-0.85). EDV, ESV, EF and MM values were significantly and positively correlated to the degree of coronary artery stenosis (r=0.21, 0.45, 0.49, 0.45, P<0.05). There was no significant difference between groups in SV value, and the extent of coronary stenosis was of no correlation (r=0.07, P>0.07). Conclusion 64-slice dynamic volume CT delivers high feasibility in simultaneously assessing functions of coronary artery stenosis and left ventricular, this technique can accurately the damage of evaluate coronary stenosis on cardiac function of left ventricular, greater damage of left ventricular function will be when the degree of coronary artery stenosis is heavier, providing important basis for clinical treatment.