Hemodynamics of the stomach |
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| Authors: | Eugene D. Jacobson M.D. Jerry B. Scott M.S. Edward D. Frohlich M.D. |
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| Affiliation: | (1) Present address: U. S. Army Research Institute of Environmental Medicine, Natick, Mass.;(2) Present address: Department of Physiology, School of Medicine, University of Oklahoma, Oklahoma City, Okla.;(3) Present address: V. A. Research Hospital, Chicago, Ill. |
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| Abstract: | Summary A method is described for measuring the change in blood pressure gradient across the stomach of the dog in response to changes in blood flow.In 16 dogs pressure-gradient responses were measured and vascular resistance calculated. The rise in pressure gradient was not proportionate to the increase in blood flow. Resistance, therefore, decreased as blood flow rose. The decline in resistance to increments in flow was especially marked till flow reached a rate of 60 ml./min. Beyond this flow the fall in resistance became slight. It appears that autoregulation does not occur to any appreciable degree in the gastric vascular bed.When flow was lowered over the same range used in raising flow, pressure values somewhat different were obtained, suggesting a hysteresis effect.Submitted to the Midwestern Section Meeting of the American Federation for Clinical Research, Chicago, Ill., Nov. 2, 1961.The authors are indebted to Dr. Francis J. Haddy for continued advice and criticism in the course of these investigations, and to Lyle Brown, James McGuire, Albert Malanche, and Miguel Ramirez for technical assistance. |
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