鼻咽癌放疗后口干燥症及其对生活质量的影响

目的观察鼻咽癌患者放疗后口干燥症的情况及其对日常生活的影响,探讨影响口干燥症的相关因素,以期提高鼻咽癌患者的生活质量。方法选择放疗后满1年复查的鼻咽癌患者79例,复查时进行面对面访谈方式的口干问卷调查,根据调查结果分析口干燥症的严重程度及其对生活质量的影响。结果全组口干燥症的发生率为100%,中重度发生率为74.7%,其中13.9%的患者夜晚经常喝水,74.7%的患者吃饭时需饮水,59.5%的患者感到说话困难,91.1%的患者认为日常生活明显受影响。结论鼻咽癌放疗后口干燥症的发生率较高,因此需要一种安全、简便、廉价、有效的方法治疗放疗后口干燥症,以提高患者的生活质量。

The xerostomia and its influence on quality of life of the nasopharyngeal carcinoma patients after radiotherapy

OBJECTIVE To observe xerostomia and its effect on quality of life of nasopharyngeal carcinoma patients after radiotherapy and discuss related factors that may improve the patients' quality of life. METHODS Seventy-nine nasopharyngeal carcinoma patients were given a questionnaire in clinic regarding xerostomia 1 year following radiotherapy. Its severity and effect on the quality of life were studied. RESULTS Xerostomia was found in all 79 patients. Moderate to severe xerostomia occurred in 74.7 % of the patients. Of the 79 patients, 13.9 % often drank water at night, 74.7 % needed to drink water while eating, 59.5 % felt difficulties speaking and 91.1 % thought that their daily life was effected significantly. CONCLUSION The occurrence rate of xerostomia was very high in nasopharyngeal carcinoma patients after radiotherapy. 74.7 % of the patients suffered from moderate to severe xerostomia and the daily life of the 91.1 % of patients was effected significantly.