杭州市社区人群中心性肥胖是代谢综合征的危险因素

目的探讨杭州社区人群中心性肥胖与代谢综合征（MS）患病及相关代谢异常之间的关系。方法于2007年3月至2007年11月随机抽取杭州市4个街道的4个社区18岁及以上常住居民1131例，实际调查1053例，男性542例，女性511例，平均45．6岁，进行流行病学问卷调查和体格检查，测定血压、腰围（WL）及血糖、血脂等生化指标。用SPSS11．0软件进行统计分析，采用方差分析和Pearson或Spearman相关分析方法。结果MS、中心性肥胖、高血压、糖尿病患病率分别为11．2％、23．6％、30．5％、8．5％。MS、高血压及糖尿病的患病率随WL的增加而显著上升（P〈0．05）。WL与体质指数、收缩压、舒张压、空腹血糖、血甘油三酯及血清总胆固醇正相关（r值分别为0．812、0．649、0．712、0．657、0．598、0．676），而与高密度脂蛋白负相关（r=-0．578）；WL增加与代谢指标异常数量呈显著正相关（r=0．658，P〈0．05）。结论杭州市社区人群中心性肥胖是MS发生的危险因素。

Central obesity and metabofic syndrome in community residents

Objective To assess the relationship between central obesity and metabolic syndrome （MS） in community population. Methods One thousand and fifty-three individuals aged ≥ 18 （mean, 45.6）,including 542 men and 511 women ,were recruited for questionnaire survey and medical examination from 4 communities of Hangzhou during March and November 2007. Their blood pressure, waist circumference, serum glucose, lipid profile, and other biochemical markers were measured. All data were used for variance analysis. Results The prevalence of MS, central obesity, hypertension, and diabetes mellitus （DM） was 11.2% , 23.6% , 30. 5% , and 8. 5% , respectively. The prevalence of MS, DM, and hypertension was increased with waist circumference （ P 〈 0. 05 ）. Waist circumference was positively correlated to body mass index （ BMI）, systolic blood pressure （ SBP）, diastolic blood pressure （ DSP）, fasting blood sugar, total cholesterol,and triglyceride （ r = 0. 812, 0. 649,0, 712, 0. 657, 0. 598, and 0. 676, respectively）, although negatively with high-density lipoprotein cholesterol （r = -0. 578）. Waist circumference also showed positive relationship with the number of lipid metabolism abnormity （ r = 0. 658, P 〈 0. 01 ） . Conclusion For Hangzhou community population, central obesity might be one of the risk factors of MS.