| 血浆内皮素—1和肿瘤坏死因子与急性心肌梗塞的关系 |
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| 引用本文： | 张博,李光明.血浆内皮素—1和肿瘤坏死因子与急性心肌梗塞的关系[J].标记免疫分析与临床,1997,4(2):77-80. |
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| 作者姓名： | 张博 李光明 |
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| 作者单位： | [1]武警上海决队医院心内科 [2]核医学研究所 |
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| 摘 要： | 本文对２０例急性心肌梗塞（ＡＭＩ）患者检测了血浆内皮素－１（ＥＴ－１）和肿瘤坏死因子（ＴＮＦ）的水平，结果表明，ＡＭＩ组的ＥＴ－１、ＴＮＦ均较正常对照明显升高（Ｐ〈０．００１），且二者与肌酸磷酸激酶的ＭＢ同功酶（ＰＣＫ－ＭＢ）均呈正相关（ｒ＝０．０６９８４，Ｐ〈０．００１；ｒ＝０．６０５３，Ｐ〈０．０１）。研究结果说明ＥＴ－１和ＴＮＦ参与了ＡＭＩ的病理损伤过程。
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| 关 键 词： | 内皮素1 肿瘤坏死因子 心肌梗塞 |
Changes in Endothelin-1 and Tumor Necrosis Factor in Acute Myocardial Infarction |
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| Zhang Bo, Cheng Shouke, Li Guangming,et al..Changes in Endothelin-1 and Tumor Necrosis Factor in Acute Myocardial Infarction[J].Labeled Immunoassays and Clinical Medicine,1997,4(2):77-80. |
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| Authors: | Zhang Bo Cheng Shouke Li Guangming |
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| Institution: | Zhang Bo, Cheng Shouke, Li Guangming, et al. |
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| Abstract: | Endothelin-1 (ET-1) and tumor necrosis factor (TNF)were measured in 20 patients with acute myocardial infarction (AMI)and 15 normal subjects. The results indicated that ET-1, TNF in patients with AMI were significantly higher than those of normals (P<0.001 ).ET-1 and TNF were positively correlated with MB isoenzyrne of creatine phosphokinase (CPK-MB)(r=0. 6984, P<0. 001; r=0. 6053, P<0.01). Our findings suggest that ET-1 and TNF are involved in injury caused by AMI. |
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| Keywords: | Endothelin-1 Tumor necrosis factor Acute myocardial infarction |
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