| 固心胶囊治疗绝经后女性冠心病及对雌激素代谢影响的临床研究 |
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| 引用本文： | 金卓祥,范书珂.固心胶囊治疗绝经后女性冠心病及对雌激素代谢影响的临床研究[J].新中医,2008,40(12). |
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| 作者姓名： | 金卓祥 范书珂 |
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| 作者单位： | 广东省中医院心脏中心; |
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| 摘 要： | 目的:观察固心胶囊治疗绝经后女性冠心病的-临床疗效,并观察其对雌二醇(E2)的影响.方法:40例气虚血瘀型患者随机分为2组,对照组20例予冠心病基础治疗配合瓜蒌薤白半夏汤口服;试验组20例在对照组治疗的基础上加服固心胶囊,疗程均为4周.结果:心绞痛疗效:总有效率试验组为95.0%,对照组为80.0%,2组比较,差异有显著性意义(P＜0.05).2组治疗后心绞痛发作频率、持续时间均较治疗前显著减少,差异有非常显著性意义(P＜0.01);试验组改善优于对照组,差异有显著性或非常显著性意义(P＜0.05,P＜0.01).硝酸甘油停减率试验组为85.0%,对照为50.0%,2组比较,差异有非常显著性意义(P＜0.01).中医证候总疗效比较:总有效率试验组为95.0%,对照组为75.0%,2组比较,差异有非常显著性意义(P＜0.01).治疗后试验组E2水平明显升高,与治疗前及对照组治疗后比较,差异均有非常显著性意义(P＜0.01).结论:固心胶囊对绝经后女性冠心病有较显著的疗效,能改善雌激素水平,这可能是其作用机制之一.
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| 关 键 词： | 冠心病 绝经后 中医疗法 固心胶囊 |
Effect of Guxtn Capsuies for the Treatment of Postmenopausal Coronary Heart Disease and on Estrogen Metabolism |
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| JIN Zhuoxiang FAN Shuke.Effect of Guxtn Capsuies for the Treatment of Postmenopausal Coronary Heart Disease and on Estrogen Metabolism[J].New Journal of Traditional Chinese Medicine,2008,40(12). |
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| Authors: | JIN Zhuoxiang FAN Shuke |
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| Abstract: | Objective:To investigate the therapeutic effect of Guxin Cap- sules (GC) for the treatment of poatmenopausal coronary heart disease and to observe its effect on eatrogen metabolism.Methods:Forty pestmenopausal coronary heart disease patients with Qi deficiency and blood stasis were equally randomized into 2 groups.The two groups received western routine medicine for coronary disease,and the control group received Gualou Xiebai Banxia Decoc- tion additionally,and the treatment group treated with Gualou Xieba... |
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| Keywords: | E2 |
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