应用超声背向散射积分评价高脂血症患者颈动脉粥样硬化

目的 ： 探讨超声背向散射积分（IBS）技术对高血脂患者早期动脉粥样硬化(atherosclerosis, AS)的诊断价值。方法 ： 对98例中青年高血脂（高血脂组）患者和51例正常人（正常组）的颈动脉多部位多点进行IBS检测。 结果 ： 高血脂组颈动脉窦部(CSA)及颈内动脉（ICA）处C-IBS均低于正常组(P<0.05) ，高血脂组与正常组颈总动脉（CCA）处C-IBS比较差异无显著性(P>0.05)。高血脂组颈动脉不同部位即CSA与CCA、CSA与ICA处C-IBS比较差异均有显著性(P<0.05)；正常组内CSA与CCA、CSA与ICA处C-IBS比较差异均无显著性(P>0.05)。结论： IBS技术可以反映血管壁的组织结构改变，为临床提供一种新的、无创性、简便易行的检测早期AS的方法。

Evaluation of quantitative ultrasonic integrated backscatter on carotida therosclerosis in hyperlipemia patients

Objective To explore the diagnostic value of integrated backscatter (IBS) technique for carotid artery atherosclerosis (AS) in hyperlipemia patients.Methods The calibrated IBS (C-IBS, C-IBS=intima-media IBS-adventitia IBS) was used to detect the carotid intima-media in the different section in 51 normal controls and 98 patients with hyperlipemias. Results The C-IBS in hyperlipemia group was lower than that in normal control, there significant difference of C-IBS between carotid sinus artery( CSA) and internal carotid artery (ICA)(P<0.05), the C-IBS of common carotid artery(CCA) in hyperlipemia group was lower than that in normal control, but no significant differentce(P>0.05).In hyperlipemia group ,there were significant differences of C-IBS between CCA, CSA and ICA (P<0.05); and there were no significant differences of C-IBS between CSA and CCA, CSA and ICA (P>0.05). Conclusion IBS technigue can reflect the changes of tissue structure of vascular wall and provide a new ,no invasive and feasible method to evaluate AS early.