A reciprocal t(4;9)(q31;p22) in a solitary neurofibroma |
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| Authors: | Sawyer Jeffrey R Parr Lewis G Gokden Neriman Nicholas Richard W |
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| Affiliation: | Department of Pathology, University of Arkansas for Medical Sciences, 4301 West Markham Street, Little Rock, AR 72205, USA. sawyerjefferyr@uams.edu |
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| Abstract: | Cytogenetic reports of solitary neurofibromas are rare and, to our knowledge, no clonal reciprocal translocations have been reported in these tumors. Reciprocal chromosome translocations have been identified in a number of solid tumors and can have both diagnostic and prognostic significance. We report the first case of a solitary circumscribed neurofibroma with a (4;9)(q31;p22) balanced reciprocal translocation as the sole cytogenetic abnormality. |
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