胱抑素C与尿素、肌酐检测的临床应用比较

目的比较胱抑素C(CysC)、尿素(Urea)、血清肌酐(Scr)的临床应用价值。方法选择1015例CysC异常患者与Urea、Scr检测结果进行相关性分析;CysC、Urea、Scr三项指标异常结果分析及应用三项指标对高血压患者联合检测结果的相关性分析等多侧面的进行比较评价。结果CysC、Urea、Scr单项检测异常检出率男女各组分别为17.06%、4.60%、2.00%和18.89%、3.32%、3.19%;三项指标异常者均高于对照组2.68～3.98倍;高血压患者CysC、Urea、Scr异常检出率男女各组分别为22.08%、12.66%、9.76%和26.25%、8.49%、2.00%。结论CysC作为肾功能检测指标异常检出率高,方法灵敏,结果稳定,是早期肾功能损害的有价值的实验诊断指标。

THE COMPARISON ANALYSIS OF CYSTATIN C WITH UREA AND SCR IN PATIENTS WITH KIDNEY FUNCTION DETERMINATION

Objective To discuss the value using serum Cystatinc C and Urea, Scr for kidney function indexes. Methods Using the method of CysC and Urea, Scr to analyse results of kidney function determination, to compare of positive rate. Results The positive rate, including the test of CysC and Urea, Scr, were 17.06%, 4.60%, 2.00%(male group) and 18.89%, 3.32%, 3.19%(female group), respectively. In CysC positive cases, the positive rate of Urea and Scr were 17.00%,10.00% (male group) and 7.00%, 4.00%(female group) respectively. In the positive cases of three determination indexes, diseased group were higher than those of the control (2.68 to 3.98 times). In patients with hypertension, positive rate of CysC and Urea, Scr were 22.08%, 12.66%, 9.76%(male group) and 26.25%, 8.49%, 2.00%, (female group) respectively. Conclusion For the diagnosis of renal damage in early stage, sensitivity of serum CysC is better in combined comparison.