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FDG PET imaging of paragangliomas of the neck: comparison with MIBG SPET |
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| Authors: | David J. Macfarlane Barry L. Shulkin Kieran Murphy Gregory T. Wolf |
| Affiliation: | (1) Division of Nuclear Medicine, Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, Michigan, USA;(2) Department of Radiology, University of Michigan Medical Center, Ann Arbor, Michigan, USA;(3) Department of Otorhinolaryngology, University of Michigan Medical Center, Ann Arbor, Michigan, USA;(4) Present address: Department of Nuclear Medicine, Royal Brisbane Hospital, Queensland, Australia;(5) Pediatric Nuclear Medicine, University of Michigan Medical Center, MCHC F3313 Box 0229, 48109-0229 Ann Arbor, MI, USA |
| Abstract: | Two patients with cervical paragangliomas underwent positron emission tomography (PET) with 2-[18F]-fluoro-2-deoxy-D-glucose (FDG). There was marked tumor uptake and retention of FDG. Adjacent salivary gland accumulation of FDG was minimal, though quite prominent withmeta-iodobenzylguanidine. FDG PET offers another potentially useful approach to functional imaging of these uncommon tumors, independent of the presence of specific amine uptake mechanisms or cell surface receptors required by other scintigraphic techniques. |
| Keywords: | Positron emission tomography Paragangliomas 2-[18F]-Fluoro-2-deoxy- font-variant:small-caps" >d-glucose Meta-iodobenzylguanidine Single-photon emission tomography |
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