| 高效液相色谱法测定活血止痛胶囊中人参皂苷Rg1含量 |
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| 引用本文： | 阮治纲.高效液相色谱法测定活血止痛胶囊中人参皂苷Rg1含量[J].中国药业,2009,18(20):35-36. |
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| 作者姓名： | 阮治纲 |
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| 作者单位： | 浙江省舟山市食品药品检验所,浙江,定海,316000 |
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| 摘 要： | 目的建立测定活血止痛胶囊中人参皂苷Rg1含量的高效液相色谱（HPLC）法。方法采用Zorbax Extend—C18柱（150mm×4．6mm，5μm），流动相为乙腈-0．1％磷酸溶液（20：80），流速为1．0mL／min，检测波长为203nm，柱温为30℃。结果人参皂苷Rg1进样量在1．236～9．888μg（r=0．9991）范围内与峰面积线性关系良好，平均回收率为97．90％，RSD=1．03％（n=6）。结论HPLC法简便可靠、专属性强，可用于活血止痛胶囊的质量检测。
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| 关 键 词： | 活血止痛胶囊 人参皂苷Rg1 高效液相色谱法 含量 |
HPLC Determination of Ginsenoside Rg1 in Huoxue Analgesic Capsules |
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| Ruan Zhigang.HPLC Determination of Ginsenoside Rg1 in Huoxue Analgesic Capsules[J].China Pharmaceuticals,2009,18(20):35-36. |
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| Authors: | Ruan Zhigang |
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| Institution: | Ruan Zhigang (Zhoushan Institute for food and Drug Control, Dinghai, Zhejiang, China 316000) |
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| Abstract: | Objective To establish a method for the determination of ginsenoside Rg1 in Huoxue Analgesic Capsules. Methods The Zorbax Extend-C18 column （150 mm ×4.6 mm,5 μm） was used with the mobile phase of aeetonitrile-0. 1% phosphoric acid solution（20：80）,the flow rate of 1.0 mL/min, and the detecting wavelength of 203 nm. The column temperature was at 30 ℃. Results The linear range was 1. 236 - 9. 888 μg for ginsenoside Rg1（ r = 0. 999 1）. The average recovery rate of ginsenoside Rg1 was 97. 90% , RSD 1.03% （ n = 6）. Conclusion The method is simple, accurate with high specificity and good repeatability. It can be used for the quality control of Huoxue Analgesic Capsules. |
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| Keywords: | Huoxue Analgesic Capsules ginsenoside Rg1 HPLC content |
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