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帕罗西汀治疗2型糖尿病伴抑郁的研究
引用本文:宋兵福,伍毅,陈一郡,冯绮文,全彩娟,徐勤燕.帕罗西汀治疗2型糖尿病伴抑郁的研究[J].临床精神医学杂志,2007,17(3):181-182.
作者姓名:宋兵福  伍毅  陈一郡  冯绮文  全彩娟  徐勤燕
作者单位:1. 200090,上海市杨浦区精神卫生中心
2. 上海市新华医院
3. 上海市中山医院青浦分院
4. 上海市安亭医院
摘    要:目的:探讨帕罗西汀对2型糖尿病伴发抑郁患者生活质量的影响.方法:对45例2型糖尿病伴发抑郁患者给予帕罗西汀治疗.疗程12周.治疗前后分别进行汉密尔顿抑郁量表(HAMD)、汉密尔顿焦虑量表(HAMA)及健康状况调查问卷(SF-36)评定.对照组50例为不伴抑郁的糖尿病患者进行SF-36评定.结果:帕罗西汀能明显改善治疗组抑郁、焦虑症状;治疗前2型糖尿病伴抑郁患者生活质量明显低于对照组.结论:帕罗西汀能明显改善2型糖尿病伴抑郁患者的生活质量及预后.

关 键 词:帕罗西汀  2型糖尿病  抑郁  生活质量
文章编号:1005-3220(2007)03-0181-02
收稿时间:2006-06-12
修稿时间:2006-06-12

Clinical observation on type 2 diabetes mellitus accompanied with depression treated by paroxetine
SONG Bing-fu,WU Yi,CHEN Yi-jun,FENG Qi-wen,QUAN Cai-juan,XUE Qin-yan.Clinical observation on type 2 diabetes mellitus accompanied with depression treated by paroxetine[J].Journal of Clinical Psychological Medicine,2007,17(3):181-182.
Authors:SONG Bing-fu  WU Yi  CHEN Yi-jun  FENG Qi-wen  QUAN Cai-juan  XUE Qin-yan
Institution:Mental Health Center of Yangpu District , Shanghai 200090, China
Abstract:Objective:To explore the quality of life in patients with type 2 diabetes mellitus accompanied with depression treated by paroxitine.Method:Forty-five type 2 diabetes mellitus patients accompanied with depression were treated by paroxetine for 12 weeks.Hamilton depression scale(HAMD),Hamilton anxiety scale(HAMA)and the medical outcomes study 36 item short form health survey(SF-36)were used before and after treatments.50 controls were evaluated with SF-36.Results:Paroxetine significantly improved the symptoms of depression and anxiety in type 2 diabetes mellitus with depression.Quality of life in patients with type 2 diabetes mellitus accompanied with depression was significantly lower than that in controls before treatment.Conclusion:Paroxetine can significantly improve the quality of life and prognosis in patients with type 2 diabetes mellitus accompanied with depression.
Keywords:paroxetine  type 2 diabetes mellitus  depression  quality of life
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